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Epilepsy is the most common serious brain disorder that characterized by recurrent seizures. Epilepsy affects 65 million people worldwide today and about two million new cases occur each year. The most negative aspect of seizure that causes the patient couldn’t have normal life, is its sudden and incontrollable features. So, the achievement of an algorithm that is capable to predicting the occurrence of seizures would help sufferers to live a normal life safe, and they can move out of harm's way. In this study, we proposed a prediction method for absence seizures based on the time-frequency analysis and complexity measure in EEG signals of WAG/Rij rats as a valid animal model of human absence epilepsy. We investigated the changes of permutation Entropy and the wavelet power of theta frequency range, simultaneously. The proposed seizures prediction algorithm was applied to long-term EEG recordings of WAG/Rij rats. The results indicate that the algorithm successfully detected the pre-ictal state prior to onset of seizures in 210 out of 298 seizures.The dependence of accuracy, sensitivity and anticipation time of prediction algorithm on program settings and attributes of EEG recordings are discussed.In this study, we found that the measure of PE reduced in pre-ictal and ictal states of EEG signals in these rats. The reduction of complexity of EEG signals prior to onset of seizures that was demonstrated by means of PE might be indicating the neural synchronization of brain networks in WAG/Rij rats.

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This paper presents a new circuit to configure power amplifier (PA) for return-to-zero on-off-keying (RZ-OOK) transmitters. The proposed PA works as a multimode structure with configurable data rate and output power. The programmable data rate function is achieved by duty cycle adjustment of input data and producing input RZ-data by a simple circuit, which leads to a linear scale of data rate with power consumption. This implies that any desired level of output power can be transmitted with different power consumption according to the power budget. The RZ-data is also utilized to perform the output power reconfiguration. The PA represents data rate of 0.3Mb/s to 3Mb/s and it can deliver output power level from -23dBm to 0dBm. During data rate adjustment, power consumption varies from 0.099mW to 0.99mW when the output power is 0dBm. Also, PA consumes 0.07mW to 0.99mW at the output power tuning range with a data rate of 3Mb/s.